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leprae. Anin silicostudy was done to grasp the molecular interactions involving DNA gyrase and WQ compounds. WQ-3334 and WQ-3810 ended up proven to have bigger inhibitory action againstM. lepraeDNA gyrase than Other folks. Moreover, analysis working with quinolone-resistantM. lepraeDNA gyrases showed that WQ-3334 had greater inhibitory action than